Pharmaceutical Nanotechnology: Innovation and Production, 2 Volumes

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Jean Cornier, Andrew Owen, Arno Kwade, Marcel Van de Voorde
John Wiley & Sons, Feb 6, 2017 - Technology & Engineering - 775 pages
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With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book.
Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!
 

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Contents

Potential Challenges and Future Development
3
A Key to Revolutionary Progress in Pharmacy
17
From Biology to Nanotechnology
43
Understanding and Characterizing Functional Properties
63
Powerful Tools Toward Precision
81
Nanostructures in Drug Delivery
103
Physical and Chemical Characterization
135
Applications of Synchrotron
157
General Overview and Insights Into
425
An Overview of Nanoparticle Biocompatibility for Their
443
Preclinical and Clinical Pharmacology
469
Regulatory Issues in Nanomedicines
497
Social Studies of Nanopharmaceutical Research
521
Nanomedicine Biodistribution and Stability
544
NanoparticleBased Physical Methods for Medical Treatments
561
Oral Delivery
579

Overview of Techniques and Description of Established
175
Exploratory Methods for Polymeric Materials
231
Overview and Presentation of Exploratory Methods for Manufacturing
271
ScaleUp and cGMP Manufacturing of Nanodrug Delivery Systems
295
Occupational Safety and Health
331
Micro and NanoTools in Drug Discovery
357
Computational Predictive Models for Nanomedicine
379
A Systems
403
Steroidal Nanodrugs Based on Pegylated Nanoliposomes Remote
603
Steroidal Nanodrugs
619
Pulmonary Nasal
633
Neurodegenerative Diseases Alzheimers Disease
649
A Practical Guide to Translating Nanomedical Products
663
Development and Commercialization of NanocarrierBased
697
Challenges and Opportunities
735
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About the author (2017)

Jean Cornier is presently consultant to several companies in the areas of life science, new technologies and business development. He obtained his PhD from the University of Caen, France, and a MSc degree in pharmaceutical medicine from the University of Duisburg-Essen, Germany. Since 1986 he has worked in the space industry as expert in Materials and Life Science research and projects, was participant in space commercialisation initiatives supported by the European and German space agencies as well as in several EU-funded projects in biotechnology and civil security research.

Professor Arno Kwade is Head of the Center of Pharmaceutical Engineering and of the Institute of Particle Technology at the Technical University Braunschweig, Germany. After his PhD he worked nine years in industry as partner of a consulting firm for processing and handling of materials and as general manager of a medium-sized company active in materials processing. Professor Kwade is speaker of the European working party on comminution and classification and developed a course on nanomilling, taken by more than 1000 participants from different industries, among them many pharmaceutical companies.

Professor Andrew Owen holds a personal Chair in Molecular and Clinical Pharmacology at the University of Liverpool, UK. He is also affiliated to the MRC Centre for Drug Safety Science and the Wolfson Centre for Personalised Medicine. He is Chair of the British Society for Nanomedicine, is co-inventor of several patents related to nanomedicines and has contributed to over 150 publications and book chapters. He is co-founder of University commercial start-ups, a Fellow of the Royal Society of Biology, a Fellow of the British Pharmacological Society and member of the steering committee for the Academy of Pharmaceutical Sciences Nanomedicine Focus Group.

Marcel Van de Voorde has 40 years` experience in European Research Organisations including CERN-Geneva, European Commission, with 10 years at the Max Planck Institute in Stuttgart, Germany. For many years, he was involved in research and research strategies, policy and management, especially in European research institutions. He holds a Professorship at the University of Technology in Delft, the Netherlands, as well as multiple visiting professorships in Europe and worldwide. He holds a doctor honoris causa and various honorary Professorships.
He is senator of the European Academy for Sciences and Arts, in Salzburg and Fellow of the World Academy for Sciences. He is a Fellow of various scientific societies and has been decorated by the Belgian King. He has authored of multiple scientific and technical publications and co-edited multiple books in the field of nanoscience and nanotechnology.

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