Point-of-Care Diagnostics on a Chip
David Issadore, Robert M. Westervelt
Springer Science & Business Media, Jan 19, 2013 - Science - 226 pages
The topic of this book is the development of automated and inexpensive tools that transfer medical tests from a specialized clinical laboratory directly to the point of care, using biochip technology. Immediate access to medically relevant biochemical information for doctors and nurses promises to revolutionize patient care and dramatically lower costs. The miniaturization and automation of medical tests are made possible by biochip technology, that integrates advances in integrated circuits, microelectromechanical systems (MEMS), microfluidics, and electronics. The target audience for this book includes engineering and biomedical researchers who would like to develop or apply biochip technology. They can use this book as a review of the field and as a guide for the development of novel biochip technology for point of care medicine. This book can also be used as a teaching tool for engineering and biomedical students, as well as a reference for physicians and health professionals.
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1-chip system amplification Anal analysis analyte antibody antigen applications array assay beads binding biological biomarkers biomedical biomolecules biosensing biosensors Chem clinical coil compensation engine concentration cytometry Debye length detection developed dielectric dielectrophoresis disease DMFET droplets electric field electronics electroporation flow cytometer fluid fluorescence frequency function G.M. Whitesides gate insulator gate surface handheld holograms holographic imaging immobilized immunoassays integrated circuit integrated circuit/microfluidic chip interface Lab Chip label-free labeled layer lensfree magnetic field magnetic nanoparticles magnetic nanotags magnetic resonance measurement membrane method microdevices microfluidic devices microscope miniaturized MNPs molecular molecules monitoring multiplexed nanogap nanoparticles nanosensors nanowire NMR signal NMR system noise nucleic acid oligonucleotide probes on-chip optical palm system performed pixels platform POC testing point-of-care diagnostics portable protein reaction real-time sample semiconductor sensitivity sensor shown in Fig solution super-resolution superparamagnetic tags target DNA techniques temperature tomography transceiver underlap vesicle voltage VT shift