Pharmacology and abuse of cocaine, amphetamines, ecstasy and related designer drugs : a comprehensive review on their mode of action, treatment of abuse and intoxication
Covers various aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB. This work provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance
1 online resource (xi, 300 pages) : illustrations
9789048124480, 9048124484
489218895
Introduction: Incidence of illicit use of cocaine and other drugs
pt. I: How it all started with cocaine. Production of the coca leaf ; Cocaine: history of use ; Popularity of cocaine as a drug for medical treatment ; The different types of alkaloids in coca ; The making of cocaine in the jungle ; Freebase cocaine: high bioavailability with increase in potency ; Pharmacology of cocaine ; Addictive properties of cocaine: mode of action ; Cocaine intoxications: strategy for treatment ; Special pathologies in chronic cocaine use ; Summary of advanced treatment in cocaine OD ; Chronic toxicity of cocaine use ; Summary of acute-chronic effects of cocaine ; Cocaine use in pregnancy ; New options in the treatment of cocaine dependency
pt. II: Methamphetamine
an old acquaintance in new clothes. Mode of action of methamphetamine ; Pharmacology of methamphetamine ; Crystal methamphetamine ; Treatment options in methamphetamine addiction and withdrawal ; Amphetamine derivatives as appetite suppressants
pt. III: MDMA (Ecstasy): from psychotherapy to a street drug of abuse. Incidence of illicit of ecstasy ; Pharmacology of ecstasy (MDMA) ; Pharmacological effects of MDMA in man ; Pharmacokinetics of MDMA ; Appendix: Analogues of MDMA and related compounds
pt. IV: Designer drugs and their abuse. History of designer drugs ; Gamma-hydroxybutyric (GHB) acid ; The pharmacology of y-Hydroxbutyric acid (GHB) ; Use of GHB in clinical medicine ; Abuse potential and intoxication with GHB ; Benzylpiperazine (BZP) as a designer drug ; Natural products with abuse potential ; Toxicity of datura stramonium ; Dimethyltryptamine (DMT) a psychedelic ; The mushroom psilocybin with psychedelic properties ; Ibogaine, psychedelic molecule with anti-addictive properties ; Peyote, a mescaline-containing cactus ; LSD, a semisynthetic psychedelic drug ; S-MeO-DIPT, a psychedelic structurally related to psiloc(yb)in
pt. V: How to demask the patient with an aberrant use. Positive signs and symptoms of hard drug use ; Urine drug screening (UDS): identifying the person with illicit use ; Types of urine drug testing ; Type of tests for urine drug testing (UDT) ; Analysis of saliva, hair and sweat for drug testing
Appendix: Common street names of cocaine and methamphetamine used as a jargon